Gomisin N Standard
Gomisin N
CAS: 69176-52-9
Molecular Formula: C23H28O6
Gomisin N Standard - Names and Identifiers
| Name | Gomisin N |
| Synonyms | Gomisin N GOMISIN N Gomisin N Standard Benzo(3,4)cycloocta(1,2-F)(1,3)benzodioxole, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7S,13as)- |
| CAS | 69176-52-9 |
Gomisin N Standard - Physico-chemical Properties
| Molecular Formula | C23H28O6 |
| Molar Mass | 400.46 |
| Melting Point | 105-107°C |
| Boling Point | 545°C at 760mmHg |
| Specific Rotation(α) | -22～-32°(D/20℃)(c=0.25,CH3CN) |
| Solubility | Soluble in chloroform, ethyl acetate, soluble in methanol |
| Appearance | White crystal or powder |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Schisandra Schisandra chinensis. |
Gomisin N Standard - Reference
| Reference Show more | 1. Zhu Jingbo, Li, Wenyu, Xiao, Wei et al. Preparation of lignans in schisandra chinensis by two-dimensional reversed-phase liquid chromatography [J]. Chromatogram 2018 036(005):464-473. 2. [IF = 4.556] kipeum Lee et al."Golisin N from Schisandra chinensis ameriorates Lipid Accumulation and industries a Brown Fat-Like Phenotype through AMP-Activated Protein Kinase in 3T3-L1 adipotes." Int J Mol Sci. 2020 Jan;21(6):2153 |
Gomisin N Standard - Reference Information
| Plant Source: | schisandra chinensis |
| biological activity | homisin N was isolated from Schisandra chinensis, it has good sedative and hypnotic effects. Golisin N can be used for allergy-related research. Golisin N is also an anti-tumor agent that exerts an anti-tumor effect by inducing apoptosis of cancer cells. |
| Use | for content determination/identification/pharmacological experiments and other pharmacological effects: 1. Hepatoprotective effect. It has a significant preventive effect on the liver cell damage induced by galactosamine, and can reduce the GPT value by 50%. Antioxidant effect. Prevents lipid oxidation and arteriosclerosis. Its antioxidant activity is better than DL-α-tocopherol. 3. Calcium antagonist action (hypotensive) and smooth muscle relaxant action. The IC50 (μm) for Ca2 + and PGF2α induced dog mesenteric artery contraction were 110 and 60, respectively. 4. Lipid metabolism promoter. |
Last Update：2024-04-10 22:29:15
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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